C43H55N4O10P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methox yethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1- methylethyl)phosphor amidite] (ACI)

hua

C43H55N4O10P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methox yethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1- methylethyl)phosphor amidite] (ACI)

Mōhiohio Taketake:


Taipitopito Hua

Tohu Hua

Taipitopito Matū

Tau Rehita CAS

163878-63-5

H302

Nga Ahuatanga Tinana Matua Uara Tikanga
Taumaha rāpoi 818.89 -
pKa (I matapaetia) 9.55±0.10 Te Mahana Waiwawa Nui: 25 °C

Ētahi atu Ingoa me nga Kaitohu

Nga Ataata Canonical

N#CCCOP(OC1C(OC(N2C=C(C(=O)NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5= CC=C(OC)C=C5)N(C(C)C)C(C)C

NGĀ ATA ISOMERIKA

C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@ H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC =C(OC)C=C4)C5= CC=CC=C5

InChI

InChI= 1S/C43H55N4O10P/c1-29(2)47(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26- 25-50-6)46-27-31(5)40(48)45-42(46)49)2 8-54-43(32-13-10-9-11-14-32,33-15 -19-35(51-7)20-16-33)34-17-21-36(52-8)22-18-34/h9-11,13-22,27,29-30,37-39 ,41H,12,24-26,28H2, 1-8H3,(H,45,48,49)/t37-,38-,39-,41-,58?/m1/s1

Kī InChI

YFRRKZDUDXHJNC-KZQAAKLLSA-N

17 Ētahi atu Ingoa mō tēnei Matū

Uridine, 5′-O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methoxyethyl)- 5-methyl-, 3′ - [2-cyanoethyl bis(1-methylethyl)phosphor

amidite] (9CI); 10: PN: US20030212017 PAGE: 18 kerēme RNA; 11: PN: US20030211606 PAGE: 18 kerēme RNA; 13: PN: US20040

005569 PAGE: 21 i kii he RNA; 13: PN: US20040006030 PAGE: 22 kerēme RNA; 13: PN: US20040014048 PAGE: 19 i kii te RNA; 13: PN: US20040014049 PAGE: 19 i kii te RNA; 14: PN: US20030198965 PAGE: 19 i kii te RNA; 14: PN: US20040005565 PAGE: 17- 22 kerēme RNA; 14: PN: US20040005570 PAGE: 19 i kii te RNA; 14: PN: US20040014047 PAGE: 19 i kii te RNA; 14: PN: US20040

014699 PAGE: 19 i kii te RNA; 15: PN: US20040014050 PAGE: 19 i kii te RNA; 15: PN: US20040014051 PAGE: 21 kerēme RNA; 15:

PN: WO03106645 PAGE: 69 i kii he RNA; 16: PN: US20040006029 PAGE: 22 kerēme RNA; 87: PN: US20040005707 PAGE: 19 i kii he RNA

Spectra Whakamatau

Kei te waatea te Spectra
1 H NMR
13 C NMR
Hetero NMR

Nga Taonga Matapae

Nga rawa e waatea ana
Koiora
Te matū
Lipinski
Hanganga e Pa ana

Koiora

Taonga Uara Tikanga Puna
Tauwehe Bioconcentration 348 pH 1; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 2810 pH 2; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 21100 pH 3; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 63100 pH 4; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 78800 pH 5; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 80800 pH 6; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 80800 pH 7; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 78800 pH 8; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 63400 pH 9; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 21800 pH 10; Te Mamahana: 25 °C (1) ACD

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Te matū

Taonga Uara Tikanga Puna
Koc 487 pH 1; Te Mamahana: 25 °C (1) ACD
Koc 3940 pH 2; Te Mamahana: 25 °C (1) ACD
Koc 29600 pH 3; Te Mamahana: 25 °C (1) ACD
Koc 88400 pH 4; Te Mamahana: 25 °C (1) ACD

 

Taonga Uara Tikanga Puna
Koc 1.10 x 105 pH 5; Te Mamahana: 25 °C (1) ACD
Koc 1.13 x 105 pH 6; Te Mamahana: 25 °C (1) ACD
Koc 1.13 x 105 pH 7; Te Mamahana: 25 °C (1) ACD
Koc 1.10 x 105 pH 8; Te Mamahana: 25 °C (1) ACD
Koc 88800 pH 9; Te Mamahana: 25 °C (1) ACD
Koc 30600 pH 10; Te Mamahana: 25 °C (1) ACD
rangitakiD 4.39 pH 1; Te Mamahana: 25 °C (1) ACD
rangitakiD 5.30 pH 2; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.18 pH 3; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.65 pH 4; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.75 pH 5; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.76 pH 6; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.76 pH 7; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.75 pH 8; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.65 pH 9; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.19 pH 10; Te Mamahana: 25 °C (1) ACD
rangitakiP 6.761±0.669 Te Mamahana: 25 °C (1) ACD
Te Wairewa o roto 2.0 x 10-4 g/L Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 0.046 g/L pH 1; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 5.7 x 10-3 g/L pH 2; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 7.6 x 10-4 g/L pH 3; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.5 x 10-4 g/L pH 4; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.0 x 10-4 g/L pH 5; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.0 x 10-4 g/L pH 6; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.0 x 10-4 g/L pH 7; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.0 x 10-4 g/L pH 8; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.5 x 10-4 g/L pH 9; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 7.4 x 10-4 g/L pH 10; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 2.0 x 10-4 g/L Te Wai Whakakore pH 7.00; Te Mamahana: 25 °C (1) ACD
Molar Intrinsic Solubility 2.4 x 10-7 mol/L Te Mamahana: 25 °C (1) ACD
Molar Solubility 5.6 x 10-5 mol/L pH 1; Te Mamahana: 25 °C (1) ACD
Molar Solubility 7.0 x 10-6 mol/L pH 2; Te Mamahana: 25 °C (1) ACD

 

Taonga Uara Tikanga Puna
Molar Solubility 9.3 x 10-7 mol/L pH 3; Te Mamahana: 25 °C (1) ACD
Molar Solubility 3.1 x 10-7 mol/L pH 4; Te Mamahana: 25 °C (1) ACD
Molar Solubility 2.5 x 10-7 mol/L pH 5; Te Mamahana: 25 °C (1) ACD
Molar Solubility 2.4 x 10-7 mol/L pH 6; Te Mamahana: 25 °C (1) ACD
Molar Solubility 2.4 x 10-7 mol/L pH 7; Te Mamahana: 25 °C (1) ACD
Molar Solubility 2.5 x 10-7 mol/L pH 8; Te Mamahana: 25 °C (1) ACD
Molar Solubility 3.1 x 10-7 mol/L pH 9; Te Mamahana: 25 °C (1) ACD
Molar Solubility 9.0 x 10-7 mol/L pH 10; Te Mamahana: 25 °C (1) ACD
Molar Solubility 2.4 x 10-7 mol/L Te Wai Whakakore pH 7.00; Te Mamahana: 25 °C (1) ACD
Taumaha rāpoi 818.89    
pKa 9.55±0.10 Te Mahana Waiwawa Nui: 25 °C (1) ACD
pKa 3.45±0.70 Te Mahana Matua: 25 °C (1) ACD

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Lipinski

Taonga Uara Tikanga Puna
Nga here e taea te huri noa 21   (1) ACD
H Nga Kaiwhiwhi 14   (1) ACD
H Nga Kaituku 1   (1) ACD
H Tapeke Kaituku/Kaiwhiwhi 15   (1) ACD
rangitakiP 6.761±0.669 Te Mamahana: 25 °C (1) ACD
Taumaha rāpoi 818.89    

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Hanganga e Pa ana

Taonga Uara Puna Tikanga
Rohe Mata Polar 164 A2 (1) ACD

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Tohua Matapae

Kei te waatea te Spectra
1 H NMR
13 C NMR

Nga korero morearea a GHS

Puna Tauākī Pūmate Waehere
H302 He kino ki te horomia Te Tari Matū a te Pakeha (ECHA) Whakarōpū me te Tapanga

Inventory - Whakamōhiotanga whakarōpūtanga me te tapanga - te nuinga o nga whakamohiotanga, European Chemical Agency (ECHA)

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