C47H60N7O10P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2- methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N ,N-bis (1-methylethyl)phosphoramidite] (ACI)

hua

C47H60N7O10P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2- methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N ,N-bis (1-methylethyl)phosphoramidite] (ACI)

Mōhiohio Taketake:


Taipitopito Hua

Tohu Hua

Taipitopito Matū

Tau Rehita CAS

251647-55-9

H302

Nga Ahuatanga Tinana Matua Uara Tikanga
Taumaha rāpoi 914.00 -
pKa (I matapaetia) 9.16±0.20 Te Mahana Waiwawa Nui: 25 °C

Ētahi atu Ingoa me nga Kaitohu

Nga Ataata Canonical

N#CCCOP(OC1C(OC(N2C= NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC =C(OC)C=C5)C6=CC=C(OC)C=C6) N(C(C)C)C(C)C

NGĀ ATA ISOMERIKA

C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@ H](O1)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C (OC)C=C4)(C5 =CC=C(OC)C=C5)C6=CC=CC=C6

InChI

InChI= 1S/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(60-27- 26-57-7)40(64-65(62-25-13-24-48)54(31(3)4)32(5)6)38(63-45)28-61-47(33- 14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10- 12,14-23,29-32,38 ,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41- ,45-,65?/m1/s1

Kī InChI

LADCDGNEBIQAAU-SBCRAQIVSA-N

17 Ētahi atu Ingoa mō tēnei Matū

Guanosine, 5′-O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ - [2-cyanoethyl bis(1- methylethyl)phosphoramidi] (9CI); 17: PN: US20030212017 PAGE: 20 te raupapa i kii; 18: PN: US20030211606 PAGE: 20

raupapa e kii ana; 19: PN: US20040005569 PAGE: 22 te raupapa i kii; 21: PN: US20040006030 PAGE: 23 te raupapa i kii; 21: PN: US20040014047 PAGE: 21 kereme raupapa; 21: PN: US20040014049 PAGE: 21 kereme raupapa; 22: PN: US20030198965 PAG

E: 20 te raupapa i kii; 22: PN: US20040005570 PAGE: 21 te raupapa i kii; 22: PN: US20040014048 PAGE: 21 te raupapa i kii;

22: PN: US20040014050 PAGE: 21 te raupapa i kii; 23: PN: US20040005565 PAGE: 17- 22 raupapa i kii; 23: PN: US20040

014051 PAGE: 23 kereme raupapa; 24: PN: US20040014699 PAGE: 21 kereme raupapa; 25: PN: US20040006029 PAGE: 23 te raupapa i kii; 25: PN: WO03106645 PAGE: 73 kereme raupapa; 96: PN: US20040005707 PAGE: 21 kereme raupapa

Spectra Whakamatau

Kei te waatea te Spectra
13 C NMR
Hetero NMR

Nga Taonga Matapae

Nga rawa e waatea ana
Koiora
Te matū
Lipinski
Hanganga e Pa ana

Koiora

Taonga Uara Tikanga Puna
Tauwehe Bioconcentration 121 pH 1; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 2580 pH 2; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 23500 pH 3; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 71800 pH 4; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 89800 pH 5; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 92100 pH 6; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 91300 pH 7; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 82500 pH 8; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 42200 pH 9; Te Mamahana: 25 °C (1) ACD
Tauwehe Bioconcentration 7860 pH 10; Te Mamahana: 25 °C (1) ACD

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Te matū

Taonga Uara Tikanga Puna
Koc 164 pH 1; Te Mamahana: 25 °C (1) ACD
Koc 3480 pH 2; Te Mamahana: 25 °C (1) ACD
Koc 31700 pH 3; Te Mamahana: 25 °C (1) ACD
Koc 96900 pH 4; Te Mamahana: 25 °C (1) ACD
Koc 1.21 x 105 pH 5; Te Mamahana: 25 °C (1) ACD

 

Taonga Uara Tikanga Puna
Koc 1.24 x 105 pH 6; Te Mamahana: 25 °C (1) ACD
Koc 1.23 x 105 pH 7; Te Mamahana: 25 °C (1) ACD
Koc 1.11 x 105 pH 8; Te Mamahana: 25 °C (1) ACD
Koc 56900 pH 9; Te Mamahana: 25 °C (1) ACD
Koc 10600 pH 10; Te Mamahana: 25 °C (1) ACD
rangitakiD 3.95 pH 1; Te Mamahana: 25 °C (1) ACD
rangitakiD 5.28 pH 2; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.24 pH 3; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.73 pH 4; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.82 pH 5; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.83 pH 6; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.83 pH 7; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.79 pH 8; Te Mamahana: 25 °C (1) ACD
rangitakiD 6.50 pH 9; Te Mamahana: 25 °C (1) ACD
rangitakiD 5.77 pH 10; Te Mamahana: 25 °C (1) ACD
rangitakiP 6.837±0.764 Te Mamahana: 25 °C (1) ACD
Te Wairewa o roto 4.4 x 10-4 g/L Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 0.34 g/L pH 1; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 0.016 g/L pH 2; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 1.7 x 10-3 g/L pH 3; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 5.7 x 10-4 g/L pH 4; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 4.6 x 10-4 g/L pH 5; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 4.4 x 10-4 g/L pH 6; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 4.5 x 10-4 g/L pH 7; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 4.9 x 10-4 g/L pH 8; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 1.0 x 10-3 g/L pH 9; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 5.2 x 10-3 g/L pH 10; Te Mamahana: 25 °C (1) ACD
Wairewa Papatipu 4.5 x 10-4 g/L Te Wai Kore Kore Te pH 6.99; Te Mamahana: 25 °C (1) ACD
Molar Intrinsic Solubility 4.8 x 10-7 mol/L Te Mamahana: 25 °C (1) ACD
Molar Solubility 3.7 x 10-4 mol/L pH 1; Te Mamahana: 25 °C (1) ACD
Molar Solubility 1.7 x 10-5 mol/L pH 2; Te Mamahana: 25 °C (1) ACD
Molar Solubility 1.9 x 10-6 mol/L pH 3; Te Mamahana: 25 °C (1) ACD

 

Taonga Uara Tikanga Puna
Molar Solubility 6.2 x 10-7 mol/L pH 4; Te Mamahana: 25 °C (1) ACD
Molar Solubility 5.0 x 10-7 mol/L pH 5; Te Mamahana: 25 °C (1) ACD
Molar Solubility 4.8 x 10-7 mol/L pH 6; Te Mamahana: 25 °C (1) ACD
Molar Solubility 4.9 x 10-7 mol/L pH 7; Te Mamahana: 25 °C (1) ACD
Molar Solubility 5.4 x 10-7 mol/L pH 8; Te Mamahana: 25 °C (1) ACD
Molar Solubility 1.1 x 10-6 mol/L pH 9; Te Mamahana: 25 °C (1) ACD
Molar Solubility 5.7 x 10-6 mol/L pH 10; Te Mamahana: 25 °C (1) ACD
Molar Solubility 4.9 x 10-7 mol/L Te Wai Kore Kore Te pH 6.99; Te Mamahana: 25 °C (1) ACD
Taumaha rāpoi 914.00    
pKa 9.16±0.20 Te Mahana Waiwawa Nui: 25 °C (1) ACD
pKa 3.45±0.70 Te Mahana Matua: 25 °C (1) ACD

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Lipinski

Taonga Uara Tikanga Puna
Nga here e taea te huri noa 22   (1) ACD
H Nga Kaiwhiwhi 17   (1) ACD
H Nga Kaituku 2   (1) ACD
H Tapeke Kaituku/Kaiwhiwhi 19   (1) ACD
rangitakiP 6.837±0.764 Te Mamahana: 25 °C (1) ACD
Taumaha rāpoi 914.00    

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Hanganga e Pa ana

Taonga Uara Puna Tikanga
Rohe Mata Polar 203 A2 (1) ACD

(1) I tatauhia ma te whakamahi i te Whanaketanga Matū Ake (ACD/Labs) Pūmanawa V11.02 (© 1994-2023 ACD/Labs)

Tohua Matapae

Kei te waatea te Spectra
1 H NMR
13 C NMR

Nga korero morearea a GHS

Puna Tauākī Pūmate Waehere
H302 He kino ki te horomia Te Tari Matū a te Pakeha (ECHA) Whakarōpū me te Tapanga

Inventory - Whakamōhiotanga whakarōpūtanga me te tapanga - te nuinga o nga whakamohiotanga, European Chemical Agency (ECHA)

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