Sulfamethazine
Mōhiohio Taketake:
Ingoa Hua: Sulfamethazine
Ingoa ingoa: sulfadimethylpyrimidine
tātai matū: C12H14N4O2S
tātai hanganga:
Te taumaha ngota: 278.33
Te nama takiuru CAS: 57-68-1
Tau whakauru EINECS: 200-346-4
Ngā āhuatanga ā-tinana me te matū
Kiato: 1.392g/cm3
Ira whakarewa: 197°C
Ira kohua: 526.2ºC
Ira hiko: 272.1ºC
Te ahua: te paura tioata ma
Wairewa: tata korekore ki te wai, kore e rewa i roto i te etera, ngawari ki te wairewa ki te waikawa waimeha, wairewa kawakore ranei.
Ko te Sulfadiazine he paturopi sulfanilamide me te tuāwhiorangi antibacterial rite ki te sulfadiazine. He pānga antibacterial i runga i te huakita enterobacteriaceae pērā i te Staphylococcus aureus kore-zymogenic, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, me ētahi atu Neisseria gonorrhoea, Neisseria meningitidis me Haemophilus influenzae. Heoi, ka piki ake te aukati huakita ki te hua, ina koa te streptococcus, Neisseria me Enterobacteriaceae huakita. Ko nga Sulfonamides he maatete bacteriostatic whanui whanui, he rite te hanganga ki te waikawa p-aminobenzoic (PABA), ka taea te mahi whakataetae i runga i te synthetase dihydrofolate i roto i nga huakita, na reira ka kore e whakamahia te PABA hei rauemi mata ki te whakahiato folate e hiahiatia ana e te huakita me te whakaiti i te nui o te huakita. tetrahydrofolate kaha metabolicly. Ko te mea whakamutunga he mea tino nui mo te whakahiato o nga purines, nga nucleosides thymidine me te waikawa deoxyribonucleic (DNA), na reira ka aukati i te tipu me te whakaputa uri o te huakita.
Ka whakamahia te nuinga mo nga mate ngawari i puta mai i nga huakita tairongo, penei i te mate mimi o raro o raro, te otitis media me te mate kiri kiri.
