7-Amino-3-cephem-4-carboxylic acid
Mōhiohio Taketake:
ingoa reo Ingarihi:
7-ANCA;7-AMOCA;(6R,7R)-7-AMino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicAcid;7-NACA;7- NACA、7-ANCA;7-ANCAChemicalbook poke;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid
Nama CAS: 36923-17-8
tātai rāpoi: C7H8N2O3S
Te taumaha ngota: 200.21
Nama EINECS: 609-312-7
tātai hanganga:
Ngā kāwai e pā ana: Ngā takawaenga pararopi;Nga takawaenga rongoa;Nga rauemi mata rongoa.
Ira whakarewa: 215-218°C
Ira kohua: 536.9±50.0 °C(I Matapae)
Kiato: 1.69± 0.1g /cm3(Whakaahua)
Taupū Reractive: 1.735 (whakatau tata)
Ira hiko: 278.508°C
Wairewa: Ka whakarewahia i roto i te wairewa wai waikawa (te paku, te wera), te DMSO (te paku).Ngā Āhuatanga: Te paura tioata ma, te ma ranei.
Te pehanga kohu: 0mmHg i te 25°C
| whakaritenga | wae | paerewa |
| Te ahua | Te paura tioata ma ranei | |
| Te ihirangi matua | % | ≥98.5% |
| makuku | % | ≤1 |
| Mono ranu | % | ≤0.5 |
| Kapoka katoa | % | ≤1 |
Cephalosporin, whakamahia hei takawaenga o te cefbutan me te cefazoxime.
Ko te waikawa sulfuric (104.3mL, 1.92mol) kua whakauruhia ki roto i nga ipu e toru, katahi ka tapirihia te waikawa isophthalic (40g, 0.24mol), ka whakakorikoria, ka whakamahana ki te 60 ℃, ka mau mo te 0.5h, me te 60% waikawa nitric (37.8g, 0.36). mol) i tapirihia ki te whakahaere i te tohu whakatere topata.Tāpirihia i roto i te 2 haora.I muri i te taapiri, te tauhohenga tiaki wera i te 60 ℃ mo te 2 haora.Matao ki raro iho i te 50 ° C, katahi ka tapirihia te 100mL wai.I whakamataohia te rauemi ki te pāmahana rūma, ringihia ki roto i te tātari, maminga ki te tango i te waikawa para, ka horoia te keke tātari ki te wai, ka whakahekehia ki te rerystallize, a ko te hua ma he 34.6 karamu, ko te hua ko te 68.4%.
20Kg, 25Kg/ peere, peere kaata, kapi ki te paparanga ma me te putea polyethylene pango.2 ℃-8 ℃ maroke, wahi raumati, tawhiti atu i te rokiroki marama, whai mana mo te 2 tau.
